All those uncomfortable conversations parents hate to have with their kids about hygiene, puberty, sex, and drugs? Beth Casey has them every day with students at Shaker Middle School.

Clark Pope not only runs a busy catering company, he's also the founder and creative force behind Pope's Kitchen.

Anthony Vicente specializes in creating fresh, delicious, and made-to-order cuisine for his clients.

La Sorella's Lisa Gerteis believes in making every meal special.

Sugar Arts Bakehouse offers a (very) personal touch.

Penny Parker’s cookies are enjoyed by lucky recipients across the country.

Brian Grimberg's low-cost, rapid detection device to diagnose malaria could save many thousands of lives in the developing world.

Dr. Charles Modlin is on the front lines of the effort to address minority health discrepancies.

The president of University Hospitals Harrington Heart and Vascular Institute Costa is also UH’s Chief Innovation Officer, due to his passion for research and technology.

Insight Clinical Trials, an independent research facility in Shaker, conducts studies on therapies that target dementia and Alzheimer’s.